Pyridone 6

Vendor: Abmole

Type: Molecular

SKU: M3737

$264.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Pyridone 6 is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK1 (IC50 = 15 nM for murine JAK1), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM), and Tyk 2 (IC50 = 1 nM) (Janus protein tyrosine kinases).
Casnumber
457081-03-7
Formula
C18H16FN3O
Mw
309.34
Psmiles
CC(C)(C)C1=NC2=C([NH]1)C3=CC=C(F)C=C3C4=C2C=CNC4=O
Purity
98.84%
Solubility
DMSO 5 mg/mL
Target synonyms
Merck-5, CMP 6, JAK Inhibitor I
Pyridone 6

Pyridone 6

$264.50 USD