(R)-Elagolix

Vendor: Abmole

Type: Molecular

SKU: M30666

$161.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Elagolix is a highly potent, selective, orally-active, short-duration, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM). Target: GnRH in vitro: Elagolix is a short-acting, nonpeptide, GnRH antagonist, administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses. Elagolix is regarded as the frontrunner of a new class of GnRH inhibitors that have been denoted as second-generation, due to their non-peptide nature and oral bioavailability.
Casnumber
834153-87-6
Formula
C32H30F5N3O5
Mw
631.59
Psmiles
CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)CC(C3=CC=CC=C3)NCCCC(=O)O)C4=C(C(=CC=C4)OC)F
Purity
≥98.0%
Solubility
DMSO ≥ 100 mg/mL
Target synonyms
NBI-56418
(R)-Elagolix

(R)-Elagolix

$161.00 USD