Rad50 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3306
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus . Chromosome, telomere . Chromosome . Localizes to discrete nuclear foci after treatment with genotoxic agents. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
10111
Human swiss prot no
Q92878
Immunogen
The antiserum was produced against synthesized peptide derived from human RAD50. AA range:681-730
Isotype
IgG
Observed band
153kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
RAD50 double strand break repair protein(RAD50) Homo sapiens The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010],
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More Info
More Info
Rad50 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
