Raf-B rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3316
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus . Cytoplasm . Cell membrane . Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
673
Human swiss prot no
P15056
Immunogen
The antiserum was produced against synthesized peptide derived from human B-RAF. AA range:576-625
Isotype
IgG
Observed band
85kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008],
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More Info
More Info
Raf-B rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
