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Rebamipide

Rebamipide

Regular price $57.50 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Rebamipide (OPC12759) is a cholecystokinin-1 (CCK1) receptor inhibitor that inhibits [125I]BH-CCK-8S with an IC50 of 37.7 μM. Rebamipide is an orally effective gastroprotective agent. Rebamipide enhances the production of endogenous PGs (particularly intragastric PGE2) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide also has anti-proliferative activity against gastric cancer cells.
Casnumber
90098-04-7
Formula
C19H15ClN2O4
Mw
370.79
Psmiles
OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C3=CC=C(Cl)C=C3
Purity
99.91%
Solubility
74 mg/mL in DMSO
Target synonyms
OPC-12759
Technical documents

Documents

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