Recombinant 2019-nCoV S Protein NTD (C-6His)

Name: Recombinant 2019-nCoV S Protein NTD (C-6His)
Brand: ELK Biotechnology
Price: 399.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: EPT165

$399.00 USD

Shipping calculated at checkout.

Documents

Manuals

Available in stock (100)

Customs clearance fees may apply
Worldwide shipping available.

For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Accession

QHD43416.1

Apparent molecular weight

40-70kDa, reducing conditions

Delivery condition

The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.

Description

Recombinant SARS-CoV-2 S Protein NTD is produced by our Mammalian expression system and the target gene encoding Gln14-Asp290 is expressed with a 6His tag at the C-terminus.

Molecular weight

32.4kDa

Other names

NA

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Storage

Reconstituted protein solution should be stored at ≤ -20°C.

Background

The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Recombinant 2019-nCoV S Protein NTD (C-6His)

Documents

Product Overview

Background

Documents

Documents

Product Citations

More Info