Recombinant Human MMP-9 (C-6His)
Vendor: ELK Biotechnology
SKU: EPT028
Regular price
$279.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Accession
AAH06093.1
Apparent molecular weight
90 KDa, reducing conditions
Delivery condition
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Description
Recombinant Human Matrix Metalloproteinase-9 is produced by our Mammalian expression system and the target gene encoding Ala19-Asp707 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA for an activated form.
Endotoxin
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Molecular weight
77.4 KDa
Other names
Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Background
Background
Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis.
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Product Citations
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More Info
More Info
Recombinant Human MMP-9 (C-6His)
Regular price
$279.00 USD
Sale price
Regular price
Unit price
/per

