Recombinant Human OX40L (C-mFc)

Item number: EPT015
Availability: In Stock
$199.00
$199.00
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Size: 10ug
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Recombinant Human OX40L (C-mFc)

Recombinant Human OX40L (C-mFc)

$199.00

Recombinant Human OX40L (C-mFc)

$199.00
Size: 10ug
Description
Recombinant Human OX40 Ligand is produced by our Mammalian expression system and the target gene encoding Gln51-Leu183 is expressed with a mFc tag at the C-terminus.
Accession
P23510
Molecular weight
42.2 KDa
Apparent molecular weight
50-70 KDa, reducing conditions
Other names
Tumor necrosis factor ligand superfamily member 4; Glycoprotein Gp34; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFSF4; CD252; TXGP1
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Biological activity
Immobilized Human OX40-Fc(Cat#CK58) at 8μg/ml (100 μl/well)can bind Human OX40L-mFc(Cat#CW25).The ED50 of Human OX40L-mFc(Cat#CW25)is 18.54 ng/ml.
Redissolve
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Delivery condition
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells, T cells, dendritic cells and endothelial cells. OX40L binds to OX40 (CD134), a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional, it has been found association with systemic lupus erythematosus, no association with occurrence of atherosclerosis.

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