Recombinant Human RIPK3 Protein (E. coli, N-His)

Vendor: Abmole

Type: Proteins

SKU: M58110

$632.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
RIPK3 is a kinase that controls necroptosis and apoptosis. In necroptosis, activated by TNF-α and ZBP1, RIPK3 phosphorylates MLKL, leading to membrane damage. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental models of critical illness. RIPK3 promotes kidney tubular injury via mitochondrial dysfunction. The FAO-dependent RIPK3 mediates pathogenesis of acute lung injury.
Purity
>90%, Endotoxin < 1 EU/µg
Solubility
Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Target synonyms
RIP-like protein kinase 3; RIP3
Recombinant Human RIPK3 Protein (E. coli, N-His)

Recombinant Human RIPK3 Protein (E. coli, N-His)

$632.50 USD