Ref-1 rabbit pAb

Ref-1 rabbit pAb

Vendor: ELK Biotechnology

SKU: ES3337

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus. Nucleus, nucleolus. Nucleus speckle. Endoplasmic reticulum. Cytoplasm. Detected in the cytoplasm of B-cells stimulated to switch (By similarity). Colocalized with SIRT1 in the nucleus. Colocalized with YBX1 in nuclear speckles after genotoxic stress. Together with OGG1 is recruited to nuclear speckles in UVA-irradiated cells. Colocalized with nucleolin and NPM1 in the nucleolus. Its nucleolar localization is cell cycle dependent and requires active rRNA transcription. Colocalized with calreticulin in the endoplasmic reticulum. Translocation from the nucleus to the cytoplasm is stimulated in presence of nitric oxide (NO) and function in a CRM1-dependent manner, possibly as a consequence of demasking a nuclear export signal (amino acid position 64-80). S-nitrosylation at Cys-93 and
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
328
Human swiss prot no
P27695
Immunogen
The antiserum was produced against synthesized peptide derived from human APEX1. AA range:191-240
Isotype
IgG
Observed band
34kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Ref-1 rabbit pAb

Ref-1 rabbit pAb

$148.00 USD