Resiquimod

Vendor: Abmole

Type: Molecular

SKU: M7189

$55.20 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Resiquimod (R-848) is a agonist of Toll-like receptors 7 and 8 (TLR7/TLR8) that induces upregulation of cytokines such as TNF-α, IL-6 and IFN-α. R848 (Resiquimod) induces differential TLR7 and/or TLR8 responses in human and murine immune cells. R848 (Resiquimod) acts as a selective activating ligand for both TLR7 and TLR8 in humans but only TLR7 in mice. It activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway with the subsequent activation of the transcription factors NF-κB and interferon regulatory factor (IRF).
Casnumber
144875-48-9
Formula
C17H22N4O2
Mw
314.38
Psmiles
CCOCC1=NC2=C([N]1CC(C)(C)O)C3=C(C=CC=C3)N=C2N
Purity
99.28%
Solubility
DMSO 30 mg/mL; Ethanol 20 mg/mL
Target synonyms
R848; S28463
Resiquimod

Resiquimod

$55.20 USD