RGB-286638

Vendor: Abmole

Type: Molecular

SKU: M10879

$207.00 USD
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Coa

Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
RGB-286638 is a potent CDK inhibitor that inhibits cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 activity,IC50 1, 2, 3, 4, 5 and 5 nM, respectively, and can inhibit GSK-3β, TAK1, Jak2 and MEK1.IC50 The values are 3, 5, 50, and 54 nM, respectively.
Casnumber
784210-87-3
Formula
C29H37Cl2N7O4
Mw
618.55458
Psmiles
COCCN1CCN(CC1)CC2=CC=C(C=C2)C3=NNC4=C3C(=O)C5=C4C=CC=C5NC(=O)NN6CCOCC6.Cl.Cl
Purity
>98.0%
Solubility
DMSO ≥ 100 mg/mL
RGB-286638

RGB-286638

$207.00 USD