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RGB-286638 free base

RGB-286638 free base

Regular price $207.00 USD
Sale price Regular price

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM.
Casnumber
784210-88-4
Mw
545.63
Psmiles
COCCN1CCN(CC1)CC2=CC=C(C=C2)C3=N[NH]C4=C3C(=O)C5=C4C=CC=C5NC(=O)NN6CCOCC6
Purity
>98.0%
Solubility
DMSO 2.6 mg/mL
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