RGMC rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11203
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cell membrane ; Lipid-anchor, GPI-anchor . Also released in the extracellular space. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
148738
Human swiss prot no
Q6ZVN8
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Isotype
IgG
Observed band
46kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
hemochromatosis type 2 (juvenile)(HFE2) Homo sapiens The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq, Oct 2015],
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Product Citations
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More Info
More Info
RGMC rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
