Rheb inhibitor NR1

Vendor: Abmole

Type: Molecular

SKU: M25389

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$287.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
Rheb inhibitor NR1

Rheb inhibitor NR1

$287.50 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Rheb inhibitor NR1 is a Rheb inhibitor with an IC50 of 2.1 µM in the Rheb-IVK assay. Rheb inhibitor NR1 can directly bind Rheb in the switch II domain and selectively inhibit the activation of mechanistic target of rapamycin complex 1 (mTORC1). Rheb inhibitor NR1 does not influence mTORC2 activity.
Casnumber
2216763-38-9
Formula
C25H19BrCl2N2O3S
Mw
578.3
Psmiles
CN(C)C(=O)C1=CC=C(C=C1)CN2C(=CC3=C2C=C(C=C3Br)SC4=CC(=C(C=C4)Cl)Cl)C(=O)O
Purity
>99%
Solubility
DMSO 50 mg/mL
Technical documents

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Coa

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