Rineterkib

Rineterkib

Vendor: Abmole

Type: Molecular

SKU: M10733

$425.50 USD
$425.50 USD
Shipping calculated at checkout.

Available in stock (500)

Size: 10mg
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Rineterkib (compound B) is an orally active inhibitor of ERK1/2 that exerts an antiproliferative effect by activating mutations in the MAPK pathway. This activity is particularly associated with KRAS-mutant non-small cell lung cancer, BRAF-mutant non-small cell lung cancer, KRAS-mutant pancreatic cancer, KRAS-mutant colon cancer, and KRAS-mutant ovarian cancer.
Casnumber
1715025-32-3
Formula
C26H27BrF3N5O2
Mw
578.42
Psmiles
CNCC(C1=CC(=CC(=C1)Br)F)NC(=O)C2=C(C=C(C=C2)C3=NC(=CN=C3N)C4CCC(C(C4)F)O)F
Purity
>99%
Solubility
DMSO ≥ 150 mg/mL
Rineterkib

Rineterkib

$425.50 USD
$425.50 USD