RLX-33

Vendor: Abmole

Type: Molecular

SKU: M21591

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$517.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
RLX-33

RLX-33

$517.50 USD

THE SCIENCE, IN DETAIL

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Specifications
Bioactivity
RLX-33 is a potent and selective blood-brain barrier permeable relaxin family peptide 3 (RXFP3) antagonist that also blocks relaxin 3 (Relaxin 3) -induced ERK1/2 phosphorylation. The IC50 phosphorylated RXFP3, ERK1 and ERK2 were 2.36μM, 7.82μM and 13.86μM, respectively. RLX-33 can block the increase of food intake in rats induced by RXFP3 selective agonist R3/I5. RLX-33 can be used in the study of metabolic syndrome.
Casnumber
2784577-71-3
Formula
C24H19ClN4O4
Mw
462.89
Psmiles
C1C(CN(C1=O)CC2=CC=CO2)C(=O)NC3=CC=C(C=C3)C4=NC(=NO4)C5=CC=C(C=C5)Cl
Purity
＞99%
Solubility
DMSO ≥ 100 mg/mL
Technical documents

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Coa

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