RN139 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES13375
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
11236
Human swiss prot no
Q8WU17
Immunogen
Synthesized peptide derived from human RN139 AA range: 10-60
Isotype
IgG
Product weight
0.005kg
Reactivity
Human; Mouse
Recommended dilutions
WB 1:500-2000;IHC-p 1:50-300
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008],
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More Info
More Info
RN139 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
