RO5126766 (VS-6766)

Vendor: Abmole

Type: Molecular

SKU: M10369

$287.50 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
RO5126766 (CH5126766, VS 6766) is a first-in-class dual MEK/RAF inhibitor with IC50 values of 8.2 nM, 19 nM, 56 nM and 160 nM for BRAF V600E, BRAF, CRAF and MEK1, respectively.
Casnumber
946128-88-7
Formula
C21H18FN5O5S
Mw
471.46
Psmiles
CN[S](=O)(=O)NC1=NC=CC(=C1F)CC2=C(C)C3=CC=C(OC4=NC=CC=N4)C=C3OC2=O
Purity
>99.0%
Solubility
DMSO 90 mg/mL
Target synonyms
CH5126766; VS 6766; Avutometinib
RO5126766 (VS-6766)

RO5126766 (VS-6766)

$287.50 USD