RO8191

Vendor: Abmole

Type: Molecular

SKU: M30500

$833.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNα/β receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC50 of 200 nM for HCV replicon. RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti-HBV activity.
Casnumber
691868-88-9
Formula
C14H5F6N5O
Mw
373.21
Psmiles
C1=CC2=NC(=CN2C3=C1C(=CC(=N3)C(F)(F)F)C(F)(F)F)C4=NN=CO4
Purity
≥98.5%
Solubility
DMSO 5 mg/mL (ultrasonic and warming and heat to 60°C)
Target synonyms
CDM-3008; RO4948191
RO8191

RO8191

$833.75 USD