Rolapitant hydrochloride hydrate

Vendor: Abmole

Type: Molecular

SKU: M30886

$109.25 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model.
Casnumber
914462-92-3
Formula
C25H29ClF6N2O3
Mw
554.95
Psmiles
CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OCC2(CCC3(CCC(=O)N3)CN2)C4=CC=CC=C4.O.Cl
Purity
≥98.0%
Solubility
DMSO ≥ 20 mg/mL
Target synonyms
SCH619734 hydrochloride hydrate
Rolapitant hydrochloride hydrate

Rolapitant hydrochloride hydrate

$109.25 USD