Rosuvastatin Sodium

Vendor: Abmole

Type: Molecular

SKU: M28512

$132.25 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
Casnumber
147098-18-8
Formula
C22H27FN3NaO6S
Mw
503.52
Psmiles
CC(C)C1=NC(=NC(=C1C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C.[Na+]
Purity
≥99.0%
Solubility
DMSO 250 mg/mL (ultrasonic)
Target synonyms
ZD 4522 Sodium; X-Plended Sodium; Crestor Sodium
Rosuvastatin Sodium

Rosuvastatin Sodium

$132.25 USD