SDS-PAGE
Activity Image
Catalog Protein.JPG
SDS-PAGE
Activity Image
Catalog Protein.JPG

Recombinant Human Epithelial discoidin domain-containing receptor 1 (DDR1), partial , Active Protein

Vendor: Biomatik

Type: Proteins

SKU: RPC31069-20ug

$280.00 USD
Shipping calculated at checkout.

Documents

SDS

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Aa sequence
DMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTA
Accession number
Q08345; DDR1
Biological activity
Biologically Active
Conjugate
Unconjugated
Description
Recombinant Human Epithelial discoidin domain-containing receptor 1 (DDR1), partial , Active Protein is a purified Active Recombinant Protein.
Endotoxin
<1.0 EU/ug, by LAL method
Expiration
12 months
Expression region
21-417aa
Host
Mammalian Cells
Protein length
Partial
Purity
>95% by SDS-PAGE
Quality systems
This product is manufactured at ISO 9001 certified facilities.
Reconstitution
{"type"=>"root", "children"=>[{"type"=>"paragraph", "children"=>[{"type"=>"text", "value"=>"Refer to the datasheet/CoA included in the product pouch."}]}]}
Research area
Cancer
Restrictions
For Research Use Only. Not for use in diagnostic procedures.
Shipping conditions
Ice packs
Species
Human (Homo sapiens)
Storage
-20°C. Avoid repeated freeze/thaw cycles.
Target name
Epithelial discoidin domain-containing receptor 1 (DDR1)
Target synonyms
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix; remodeling of the extracellular matrix; cell migration; differentiation; survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2; MMP7 and MMP9; and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy; for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity) . Promotes smooth muscle cell migration; and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11
Theoretical mw
46.8kDa
SDS-PAGE

Recombinant Human Epithelial discoidin domain-containing receptor 1 (DDR1), partial , Active Protein

$280.00 USD