RPTOR rabbit pAb

RPTOR rabbit pAb

Item number: ES8990
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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RPTOR rabbit pAb

RPTOR rabbit pAb

$148.00

RPTOR rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 730-810
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
146kD
Geneid human
57521
Human swiss prot no
Q8N122
Cellular localization
Cytoplasm. Lysosome. Cytoplasmic granule . Targeting to lysosomes depends on amino acid availability. In arsenite-stressed cells, accumulates in stress granules when associated with SPAG5 and association with lysosomes is drastically decreased.
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

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