S12A1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES13272
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Apical cell membrane ; Multi-pass membrane protein .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6557
Human swiss prot no
Q13621
Immunogen
Synthesized peptide derived from human S12A1 AA range: 595-645
Isotype
IgG
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Recommended dilutions
WB 1:500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010],
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Product Citations
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More Info
More Info
S12A1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

