SAR-020106

Vendor: Abmole

Type: Molecular

SKU: M11418

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$218.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
SAR-020106

SAR-020106

$218.50 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Sar-020106 is an ATP-competitive and selective CHK1 inhibitor with an IC50 of 13.3 nM. Sar-020106 has good selectivity to CHK2. Sar-020106 increased cell lethality of Gemcitabine and SN38 by 3.0 to 29 times in a p53-dependent manner in several colon cancer cell lines. Sar-020106 can enhance antitumor activity by selecting anticancer drugs.
Casnumber
1184843-57-9
Formula
C19H19ClN6O
Mw
382.85
Psmiles
CC(CN(C)C)OC1=C(N=CC(=N1)NC2=NC=C3C(=CC=CC3=C2)Cl)C#N
Purity
>98%
Solubility
DMSO : 20 mg/mL
Technical documents

Documents

Coa

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