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SAR-441566

SAR-441566

Regular price $626.75 USD
Sale price Regular price

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
SAR-441566 is an orally active TNF-α inhibitor that blocks the interaction of TNFα with TNFR1 by distorting the conformation of the soluble TNFα trimer and does not affect signaling of TNFα bound to cell membranes, and can be used in rheumatoid arthritis-related studies.
Casnumber
2248726-53-4
Formula
C27H24F2N6O2
Mw
502.52
Psmiles
CN1C2CC(C3=C(C1=O)C=CC=C3OC(F)F)N4C2=NC5=C4C=C(C=C5)C6=CN=C(N=C6)C7(CCC7)N
Purity
>98.0%
Solubility
DMSO 100 mg/mL
Target synonyms
TNFα activity modulator 3
Technical documents

Documents

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