SAR125844

Vendor: Abmole

Type: Molecular

SKU: M20606

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$161.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
SAR125844

SAR125844

$161.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
SAR125844 is a potent intravenously active and highly selective MET kinase inhibitor, displaying nanomolar activity against the wild-type kinase (IC50 value of 4.2 nmol/L) and H1094Y, Y1235D, M1250T, L1195V, and D1228H kinase domain mutants (IC50 values of 0.22, 1.7, 6.5, 65, and 81 nmol/L, respectively).
Casnumber
1116743-46-4
Formula
C25H23FN8O2S2
Mw
550.63
Psmiles
FC1=CC=C(C=C1)C2=N[N]3C(=NN=C3C=C2)SC4=CC=C5N=C(NC(=O)NCCN6CCOCC6)SC5=C4
Purity
>98.0%
Solubility
DMSO 28 mg/mL
Technical documents

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