SD-36

Vendor: Abmole

Type: Molecular

SKU: M21159

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$920.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
SD-36

SD-36

$920.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
SD-36 is a potent STAT3 PROTAC degradation agent (Kd=~50 nM) with a high selectivity compared to other STAT members. SD-36 is composed of the STAT3 inhibitor SI-109, a linker, and an analog of Cereblon ligand Lenalidomide for E3 ubiquitin ligase.
Casnumber
2429877-44-9
Formula
C59H62F2N9O12P
Mw
1158.15
Psmiles
C1CC(N2C1CCN(CC(C2=O)NC(=O)C3=CC4=C(N3)C=CC(=C4)C(F)F)C(=O)CCCCCC#CC5=C6CN(C(=O)C6=CC=C5)C7CCC(=O)NC7=O)C(=O)NC(CCC(=O)N)C(=O)NC(C8=CC=CC=C8)C9=CC=C(C=C9)P(=O)(O)O
Purity
>99.0%
Solubility
DMSO ≥ 100 mg/mL
Technical documents

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