Vodobatinib (K0706)

Name: Vodobatinib (K0706)
Brand: Selleckchem
Price: 185.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E0047-5mg

$185.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Protein Tyrosine Kinase

Cas number

1388803-90-4

Formula

C27H20ClN3O2

Small target

Bcr-Abl

Smiles

CC1=C(C=C(C=C1)C(=O)NNC(=O)C2=C(C)C=CC=C2Cl)C#CC3=CC4=CC=CC=C4N=C3

Storage conditions

3 years -20°C powder

Synonyms

SCO-088, SUN K706, SUN-K0706

Background

Vodobatinib (K0706, SCO-088, SUN K706, SUN-K0706) is a novel BCR-ABL1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants with IC50s of 167 nM, 154 nM,165 nM and 1967 nM for BCR-ABL1L248R, BCR-ABL1Y253H , BCR-ABL1E255V and BCR-ABL1T315I, respectively.

Vodobatinib (K0706)

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Product Overview

Background

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