Vodobatinib (K0706) chemical structure

Vodobatinib (K0706)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E0047-5mg

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Vodobatinib (K0706) chemical structure

Vodobatinib (K0706)

$185.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1388803-90-4
Formula
C27H20ClN3O2
Small target
Bcr-Abl
Smiles
CC1=C(C=C(C=C1)C(=O)NNC(=O)C2=C(C)C=CC=C2Cl)C#CC3=CC4=CC=CC=C4N=C3
Storage conditions
3 years -20°C powder
Synonyms
SCO-088, SUN K706, SUN-K0706
Scientific background
Vodobatinib (K0706, SCO-088, SUN K706, SUN-K0706) is a novel BCR-ABL1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants with IC50s of 167 nM, 154 nM,165 nM and 1967 nM for BCR-ABL1L248R, BCR-ABL1Y253H , BCR-ABL1E255V and BCR-ABL1T315I, respectively.
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