2-BP (2-Bromohexadecanoic acid) chemical structure

2-BP (2-Bromohexadecanoic acid)

Vendor: Selleckchem

Type: Metabolism

SKU: E0120-5mg

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2-BP (2-Bromohexadecanoic acid) chemical structure

2-BP (2-Bromohexadecanoic acid)

$110.00 USD

THE SCIENCE, IN DETAIL

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Specifications
Big target
Metabolism
Cas number
18263-25-7
Formula
C16H31BrO2
Small target
Transferase
Smiles
CCCCCCCCCCCCCCC(Br)C(O)=O
Storage conditions
3 years -20°C powder
Synonyms
2-bromopalmitate
Scientific background
2-BP (2-Bromohexadecanoic acid) is a nonmetabolisable analogue of palmitate and acts as a palmitoylation inhibitor, which inhibits multiple palmitoyl-acyl transferase (PAT) activity towards MyrGCK(NBD) and FarnCNRas(NBD) with identical IC50s of approx. 4 µM. 2-Bromohexadecanoic acid can directly and irreversibly inhibit the palmitoyltransferase activity of all DHHC (Asp-His-His-Cys) proteins.
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