JR14a chemical structure

JR14a

Vendor: Selleckchem

Type: Immunology & Inflammation

SKU: E1048-5mg

Explore specifications & documents
$193.00 USD
Shipping calculated at checkout.

Documents

MSDS

Available in stock (500)

Request a quotation
  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.
JR14a chemical structure

JR14a

$193.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Immunology & Inflammation
Cas number
2411440-41-8
Formula
C25H26Cl2N4O3S
Small target
Complement System
Smiles
CC1=C(SC(=C1)C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)C(=O)NC(CCCNC(N)=N)C(O)=O
Storage conditions
3 years -20°C powder
Scientific background
JR14a, a selective and potent human Complement C3a receptor antagonist, which is assessed by inhibition of intracellular calcium release (IC50=10 nM) induced in human monocyte-derived macrophages by C3a, inhibition of β-hexosaminidase secretion (IC50=8 nM) from human LAD2 mast cells degranulated by C3a, and selectivity for human C3aR over C5aR.
Technical documents

Documents

MSDS

A PARTNER IN YOUR RESEARCH

More time for discovery. Less time sourcing.

Bring your laboratory requirements together with scientific advice, global sourcing and dedicated procurement support.

Explore our services

Starting a new laboratory?

Plan your laboratory with our New-Lab programme.

Discover New-Lab