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KP-457 chemical structure

KP-457

Regular price $223.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Immunology & Inflammation
Cas number
1365803-52-6
Formula
C21H24N2O7S2
Small target
Immunology & Inflammation related
Storage conditions
3 years -20°C powder
Synonyms
TNF‐α‐converting enzyme
Scientific background
KP-457 (TNF-α-converting enzyme) is a selective inhibitor of ADAM17 with IC50 of 11.1 nM/L (cell-free assay). It also cleaves various molecules such as GPIbα, GPV, and TNF-α.
Technical documents

Documents

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