DB2313

Vendor: Selleckchem

Type: Immunology & Inflammation

SKU: E1519-5mg

$148.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Immunology & Inflammation

Cas number

2170606-74-1

Formula

C42H41FN8O2

Small target

Immunology & Inflammation related

Background

DB2313 is a potent inhibitor of the transcription factor PU.1, effectively blocking PU.1-dependent reporter gene transactivation with an IC50 of 5 μM. DB2313 demonstrated significant anti-leukemic activity by inducing apoptosis in acute myeloid leukemia (AML) cells. It also increases survival rates and reduces tumor burden in vivo.

DB2313

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DB2313

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