Asundexian chemical structure

Asundexian

Vendor: Selleckchem

Type: Metabolism

SKU: E1789-5mg

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For research use only — not intended for clinical or diagnostic purposes.
Asundexian chemical structure

Asundexian

$148.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
2064121-65-7
Formula
C26H21ClF4N6O4
Small target
Factor Xa
Smiles
COC(C(C1=C(N2C=C(N=N2)C(F)(F)F)C=CC(Cl)=C1)=C3)=CN([C@@H](CC)C(NC4=CC(F)=C(C=C4)C(N)=O)=O)C3=O
Storage conditions
3 years-20°C powder 2 years-80°C in solvent
Synonyms
BAY-2433334
Scientific background
Asundexian (BAY 2433334) is an orally administered inhibitor of coagulation factor XIa (FXIa). It binds reversibly to the FXIa active site with high affinity, blocking its enzymatic function. In buffer systems, asundexian exhibits an IC50 of 1 nM against human FXIa.
Technical documents

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