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Pebezertinib chemical structure

Pebezertinib

Regular price $148.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
2769954-39-2
Formula
C24H19F4N7O
Small target
EGFR
Synonyms
LNG-451
Scientific background
Pebezertinib is a central nervous system (CNS)-penetrant, wild-type EGFR-sparing, covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM. It also exhibits a potent anti-tumor efficacy.
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