Doxorubicin chemical structure

Doxorubicin

Vendor: Selleckchem

Type: DNA Damage/DNA Repair

SKU: E2516-5mg

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Doxorubicin chemical structure

Doxorubicin

$148.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
DNA Damage/DNA Repair
Cas number
23214-92-8
Formula
C27H29NO11
Small target
Topoisomerase
Smiles
COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1
Storage conditions
3 years -20°C(in the dark) powder1 year -80°C(in the dark) in solvent
Synonyms
Adriamycin,Hydroxydaunorubicin,DOX
Scientific background
Adriamycin (Doxorubicin, Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent, inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication, and induces apoptosis, also inhibits human DNA topoisomerase I with an IC50 of 0.8 μM.
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