Avitinib maleate

Name: Avitinib maleate
Brand: Selleckchem
Price: 148.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E4597-5mg

$148.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Protein Tyrosine Kinase

Cas number

1557268-88-8

Formula

C26H26FN7O2.C4H4O4

Small target

EGFR

Synonyms

Abivertinib maleate, AC0010 maleate, AC0010MA

Background

Avitinib maleate(Abivertinib maleate, AC0010 maleate, AC0010MA) is a third-generation, irreversible, and orally active selective inhibitor of EGFR. It displays IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M, and wild-type EGFR. Avitinib maleate also acts as an inhibitor of BTK that induces apoptosis of BTK in mantle cell lymphoma.

Avitinib maleate

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Product Overview

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