Osimertinib dimesylate

Name: Osimertinib dimesylate
Brand: Selleckchem
Price: 148.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E4664-5mg

$148.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Protein Tyrosine Kinase

Cas number

2070014-82-1

Formula

C28H33N7O2.2CH4O3S

Small target

EGFR

Synonyms

Mereletinib dimesylate, AZD-9291 dimesylate

Background

Osimertinib dimesylate (Mereletinib dimesylate, AZD-9291 dimesylate) is a potent, mutant-selective, irreversible inhibitor of EGFR kinase activity with an IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. It demonstrates anti-tumor activity in xenograft and transgenic T790M EGFR mutant models, supporting its use in non-small cell lung cancer (NSCLC) research.

Osimertinib dimesylate

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Product Overview

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