MTX-531 chemical structure

MTX-531

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E4680-5mg

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MTX-531 chemical structure

MTX-531

$148.00 USD

THE SCIENCE, IN DETAIL

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Specifications
Big target
Protein Tyrosine Kinase
Cas number
2791417-66-6
Formula
C22H20ClN5O2S
Small target
EGFR
Synonyms
NSC827271
Scientific background
MTX-531(NSC827271) is a first-in-class, potent and selective inhibitor of EGFR and PI3Kα with an IC50 of 14.7 nM and 6.4 nM, respectively. It may play a role in treating Head and Neck Squamous Cell Carcinoma (HSNCC), squamous lung cancers, and certain EGFR/PI3K-driven triple-negative breast cancers.
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