MTX-531

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E4680-5mg

$148.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Protein Tyrosine Kinase

Cas number

2791417-66-6

Formula

C22H20ClN5O2S

Small target

EGFR

Synonyms

NSC827271

Background

MTX-531(NSC827271) is a first-in-class, potent and selective inhibitor of EGFR and PI3Kα with an IC50 of 14.7 nM and 6.4 nM, respectively. It may play a role in treating Head and Neck Squamous Cell Carcinoma (HSNCC), squamous lung cancers, and certain EGFR/PI3K-driven triple-negative breast cancers.

MTX-531

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