MGD-28 chemical structure

MGD-28

Vendor: Selleckchem

Type: Immunology & Inflammation

SKU: E4724-5mg

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$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
MGD-28 chemical structure

MGD-28

$148.00 USD

THE SCIENCE, IN DETAIL

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Specifications
Big target
Immunology & Inflammation
Cas number
2991818-13-2
Formula
C33H34FN7O3
Small target
Immunology & Inflammation related
Scientific background
MGD-28 is a potent and orally active degrader of Cereblon (CRBN)-dependent IKAROS proteins. It effectively degrades IKZF1 (DC50 = 3.8 nM), IKZF2 (DC50 = 56.3 nM), and IKZF3 (DC50 = 7.1 nM). It demonstrates significant antiproliferative potency across various hematologic cancer cell lines.
Technical documents

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