HS-10296 hydrochloride

Name: HS-10296 hydrochloride
Brand: Selleckchem
Price: 148.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E4886-5mg

$148.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Protein Tyrosine Kinase

Cas number

2134096-03-8

Formula

C30H35N7O2.ClH

Small target

EGFR

Synonyms

Almonertinib (hydrochloride), HS-10296 HCl

Background

HS-10296 hydrochloride(Almonertinib (hydrochloride), HS-10296 HCl) is an irreversible, third-generation inhibitor of EGFR tyrosine kinase that demonstrates high selectivity for EGFR-sensitizing mutations, T790M resistance mutation. It exhibits inhibitory activity against T790M, T790M/L858R, and T790M/Del19, with IC50 of 0.37 nM, 0.29 nM, and 0.21 nM, respectively. It also exhibits anti-tumor activity.

HS-10296 hydrochloride

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Product Overview

Background

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