HS-10296 hydrochloride chemical structure

HS-10296 hydrochloride

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E4886-5mg

Explore specifications & documents
$148.00 USD
Shipping calculated at checkout.

Documents

MSDS

Available in stock (500)

Request a quotation
  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.
HS-10296 hydrochloride chemical structure

HS-10296 hydrochloride

$148.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
2134096-03-8
Formula
C30H35N7O2.ClH
Small target
EGFR
Synonyms
Almonertinib (hydrochloride), HS-10296 HCl
Scientific background
HS-10296 hydrochloride(Almonertinib (hydrochloride), HS-10296 HCl) is an irreversible, third-generation inhibitor of EGFR tyrosine kinase that demonstrates high selectivity for EGFR-sensitizing mutations, T790M resistance mutation. It exhibits inhibitory activity against T790M, T790M/L858R, and T790M/Del19, with IC50 of 0.37 nM, 0.29 nM, and 0.21 nM, respectively. It also exhibits anti-tumor activity.
Technical documents

Documents

MSDS

A PARTNER IN YOUR RESEARCH

More time for discovery. Less time sourcing.

Bring your laboratory requirements together with scientific advice, global sourcing and dedicated procurement support.

Explore our services

Starting a new laboratory?

Plan your laboratory with our New-Lab programme.

Discover New-Lab