Dacomitinib hydrate chemical structure

Dacomitinib hydrate

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: E4904-5mg

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$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Dacomitinib hydrate chemical structure

Dacomitinib hydrate

$148.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1042385-75-0
Formula
C24H25ClFN5O2.H2O
Small target
EGFR
Synonyms
PF-00299804, PF-804
Scientific background
Dacomitinib hydrate(PF-00299804, PF-804) is an orally administered, highly selective irreversible inhibitor targeting pan-ERBB receptors, with an IC50 of 6.0 nM for EGFR, 45.7 nM for ERBB2, and 73.7 nM for ERBB4. It also demonstrates anti-tumor activity.
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