PTP1B-IN-2 chemical structure

PTP1B-IN-2

Vendor: Selleckchem

Type: Metabolism

SKU: S0119-5mg

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PTP1B-IN-2 chemical structure

PTP1B-IN-2

$298.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Metabolism
Cas number
1919853-46-5
Formula
C34H36N2O9S2
Small target
phosphatase
Smiles
CC1=CC=C(C=C1)COC2=C(C=C(C=C2)N(CC3=CC=C(C=C3)N(CC(=O)OC)S(=O)(=O)C)S(=O)(=O)CC4=CC=CC=C4)C(=O)OC
Storage conditions
3 years -20°C powder
Synonyms
MDK3465, Ptp1B-In-2, Compound P6
Scientific background
PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. PTP1B-IN-2 enhances insulin-mediated insulin receptor β (IRβ) phosphorylation and insulin-stimulated glucose uptake.
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