CS-2660 (JNJ-38158471)

Name: CS-2660 (JNJ-38158471)
Brand: Selleckchem
Price: 208.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S0377-5mg

$208.00 USD

Shipping calculated at checkout.

Documents

MSDS

Available in stock (500)

Customs clearance fees may apply
Worldwide shipping available.

For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Protein Tyrosine Kinase

Cas number

951151-97-6

Formula

C15H17ClN6O3

Small target

VEGFR

Smiles

CCNC(=O)NC1=C(C=C(C=C1)OC2=NC=NC(=C2C=NOC)N)Cl

Storage conditions

3 years -20°C powder

Background

CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as RET (c-RET) and Kit (c-Kit) with IC50 of 180 nM and 500 nM，while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3.

CS-2660 (JNJ-38158471)

Documents

Product Overview

Background

Documents

Documents

Product Citations

More Info