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Olitigaltin (TD-139) chemical structure

Olitigaltin (TD-139)

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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Immunology & Inflammation
Cas number
1450824-22-2
Formula
C28H30F2N6O8S
Small target
Galectin
Smiles
C1=CC(=CC(=C1)F)C2=CN(N=N2)C3C(C(OC(C3O)SC4C(C(C(C(O4)CO)O)N5C=C(N=N5)C6=CC(=CC=C6)F)O)CO)O
Storage conditions
3 years -20°C powder
Synonyms
GB0-139
Scientific background
Olitigaltin (TD-139, GB0-139) is a potent and selective inhibitor of galectin-3 with Kd of 0.036 µM over galectin-1 and galectin-7 with Kd of 2.2 µM and 32 µM, respectively. TD-139 is used potentially for the treatment of idiopathic pulmonary fibrosis (IPF).
Technical documents

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