SCH-23390 hydrochloride

Name: SCH-23390 hydrochloride
Brand: Selleckchem
Price: 268.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Neuronal Signaling

SKU: S0476-5mg

$268.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Neuronal Signaling

Cas number

125941-87-9

Formula

C17H19Cl2NO

Small target

Dopamine Receptor

Smiles

CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Cl.Cl

Storage conditions

3 years -20°C powder

Synonyms

R-(+)-SCH-23390 hydrochloride, SCH-23390 HCl

Background

SCH-23390 hydrochloride (R-(+)-SCH-23390, SCH-23390) is a highly potent and selective dopamine D1-like receptor antagonist with Ki of 0.2 nM and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. SCH-23390 hydrochloride is a potent and high efficacy agonist at h5-HT2C receptors with Ki of 9.3 nM. SCH-23390 hydrochloride directly inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with IC50 of 268 nM.

SCH-23390 hydrochloride

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Product Overview

Background

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