MAZ51 chemical structure

MAZ51

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S0765-5mg

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MAZ51 chemical structure

MAZ51

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
163655-37-6
Formula
C21H18N2O
Small target
VEGFR
Smiles
CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
Storage conditions
3 years -20°C powder
Scientific background
MAZ51 is a potent and selective inhibitor of vascular endothelial growth factor receptor (VEGFR)-3 (Flt-4) tyrosine kinase. MAZ51 induces cell rounding and G2/M cell cycle arrest in glioma cells through phosphorylation of Akt/GSK3β and activation of RhoA. MAZ51 inhibits the proliferation and induces the apoptosis of a variety of non-VEGFR-3-expressing tumor cell lines.
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