Danicopan chemical structure

Danicopan

Vendor: Selleckchem

Type: Immunology & Inflammation

SKU: S0803-5mg

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For research use only — not intended for clinical or diagnostic purposes.
Danicopan chemical structure

Danicopan

$313.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Immunology & Inflammation
Cas number
1903768-17-1
Formula
C26H23BrFN7O3
Small target
Complement System
Smiles
CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4CC(CC4C(=O)NC5=NC(=CC=C5)Br)F
Storage conditions
3 years -20°C powder
Synonyms
ACH-4471, ACH-0144471, ACH-CFDIS, ALXN 2040
Scientific background
Danicopan is a potent, selective and orally active inhibitor of factor D with Kd of 0.54 nM for human Factor D. Danicopan inhibits alternative pathway of complement (APC) activity, and has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
Technical documents

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