Nintedanib chemical structure

Nintedanib

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S1010-1g

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Nintedanib chemical structure

Nintedanib

$2,228.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
656247-17-5
Formula
C31H33N5O4
Small target
FGFR
Smiles
CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
Storage conditions
2 years -80 in solvent
Synonyms
BIBF 1120, Intedanib
Scientific background
Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.
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